The reason for this is that the refluxate spends very little time in the esophagus and does most of its damage in the larynx. Although some persons with LPR do suffer from heartburn or esophagitis (12%), most persons with LPR do not. They typically suffer from heartburn and many pertsons with GERD have esophagitis. Patients with GERD are usually seen by a gastroenterologist. LPR is different than gastroesophageal reflux disease (GERD). Specific findings include laryngeal hyperemia, posterior commissure hypertrophy, pseudosulcus vocalis, and thick endolaryngeal mucus. The above picture displays a diffusely inflammed larynx secondary to LPR. The damage caused by these materials can be extensive. The injurious agents in the refluxed stomach contents (refluxate) are primarily acid and activated pepsin, a proteolytic enzyme needed to digest food in the stomach. The word reflux literally means “backflow.” Laryngopharyngeal reflux, or LPR, is the backflow of stomach contents up the esophagus and into the throat.
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March 2023
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